Vibriance Super C Serum Review: A Clinician’s Review
Written By Kobi Nathan, Pharm.D., M.Ed., CDP, BCGP, AGSF
Sleep Disorders
June 29, 2023

Vibriance Super C Serum Review

This review of Vibriance Super C Serum shows that it makes questionable claims about its Vitamin C formulation.

Some ingredients have been clinically proven to improve skin elasticity and hydration.

Other ingredients may be toxic to certain individuals.

Vibriance Super C Serum is a skincare and cosmetics beauty brand marketed to women over 50.

The official website states that the Vibriance Super C Penetrating Serum is the company’s most popular product.

The brand touts its product as ” an all-in-one hydrating serum that targets age spots, wrinkles, & more…”

Let’s get down to the details because that’s why you are here:

  • Does this product really help improve your skin?
  • What are its ingredients?
  • Does the brand cite appropriate clinical studies or reputable sources, to align with its claim of “Where Science Meets Skincare?”
  • Does the product contain unhealthy or unnecessary additives?
  • What do the reviews say, and are they reputable reviews?

In this review, we’ll answer all the questions posed above.

By the end, you’ll have all the information you need to decide if this serum is right for you.

Key Takeaways

  • Certain ingredients in Vibriance Super C Serum have been proven in clinical research to improve skin hydration and reduce visible wrinkles.
  • The brand makes bold claims about its Vitamin C formulation but does not back them up with science-based evidence.
  • Additives used in the formulation are questionable, and at least two have been linked to possible toxicity.
  • There are mixed reviews, with negative reviews claiming allergic skin breakouts.

Ingredient Review

Major red flag – Questionable claim about Vitamin C

On its product page, the brand states, “It starts with the highest quality Vitamin C on the market today.”

The next statement after this assertion caught my clinically and researched-trained eye: “Our unique Vitamin C extract is shown in studies to produce far better results than standard Vitamin C.”

And that was it…no clear citation to the “studies,” or references were made.

I carefully scrolled through the page, all the way to the bottom, and I could not find any peer-reviewed scholarly article to support this claim.

The specific formulation of Vitamin C that the brand uses in this product is not clearly stated on the product page either.

The only way to get this information is to scroll all the way down to the accordion-type “Common Questions” and locate the “What is the Full Ingredient List” question:

Vibriance Super C Serum Full Ingredient List


As you can see in the list above,  3-O-Ethyl Ascorbic Acid is listed as the type of Vitamin C used in this product.

I searched the National Library of Medicine website for clinical studies supporting this type of Vitamin C as an anti-aging agent and found one clinical trial published in the journal “Life” in 2021.

This study suggests that 3-O-Ethyl Ascorbic Acid may have anti-aging activity and improve skin.

However, the Vitamin C formulation concentration used in this study was 30%.

Vibriance Super C Serum, on the other hand, does not state the strength of its 3-O-Ethyl Ascorbic Acid anywhere in the ingredient list or on the product page.

I find this to be highly questionable and a big red flag.

The other big concern I have relates to the statement from Vibriance I mentioned above: “Our unique Vitamin C extract is shown in studies to produce far better results than standard Vitamin C.”

I find this statement misleading, as I could not find ANY clinical studies doing a head-to-head comparison between standard Vitamin C and 3-O-Ethyl Ascorbic Acid.

If I made such bold, unsubstantiated statements to my healthcare colleagues, I would be laughed out of the room, and my credibility would be tarnished for good.

I do have to give some credit to several of the other ingredients in this product.

Many of them are research-backed and may have anti-aging effects on the skin.

Let’s delve into some of these ingredients:

Research-backed anti-aging ingredients in Vibriance Super C Serum

Vibriance Super C Serum does have ingredients that have strong anti-oxidative properties.

I’ll highlight the main ones below:

Sodium Hyaluronate (Hyaluronic Acid)

Abundant clinical studies show Hyaluronic acid’s positive effect on the skin.

For example, this clinical review published in the International Journal of Biological Macromolecules in 2018 showed the compound could reduce skin wrinkles.

In another study published in 2021, the authors state that “hyaluronic acid has the function of a viscosity modifier and/or a skin conditioning agent…and has the ability to enhance the level of moisture of the skin and expedite regeneration.”


Caffeine has a lot of clinical and research evidence backing its role in reducing oxidative stress-induced signs of aging on skin.

This research study verifies that caffeine protects skin from oxidative stress and activates autophagy, the process of destroying damaged or old cellular components and recycling them to create fresh, new cells.


Panthenol, or pantothenic acid, a precursor to Vitamin B5, is a great skin moisturizer with lots of science-based research backing its use in cosmetic and skincare products.

Trusted brands such as Cetaphil use it in their products.

Panthenol is both a humectant (helps skin attract water) and an emollient (softens and soothes skin).

This study is just one of many in the biomedical literature that verifies Panthenol’s positive effects on the skin.

Acetyl Glucosamine

N-acetyl glucosamine is another great ingredient for maintaining healthy, smooth skin.

This article shows how this compound promotes skin moisturization, reduces skin flakiness, and normalizes the skin exfoliation process.

Potentially toxic ingredients:


Also called TEA, triethanolamine is commonly found in many cosmetic products.

Although it is FDA-approved, a deeper review of this compound shows it is only appropriate for short, discontinuous use.

There is strong evidence that TEA is a human toxicant.

Studies on mammalian cells show that it may be cancer-causing and can cause allergic reactions, eye problems, hair and skin dryness, and can be absorbed into the body with long-term use.

This ingredient can also be found in another popular but questionable cosmetic product, Perbelle CC Cream.

Learn more about Perbelle’s product in my detailed review here.


Phenoxyethanol is a preservative in many cosmetic and skin products, including eye shadow, hand cream, shaving cream, deodorant, toothpaste, baby wipes, and many other products.

Certain individuals have developed eczema, hives, and life-threatening anaphylaxis from using it on their skin.


Vibriance Super C Serum also contains ethylhexylglycerin, another compound shown to cause allergic reactions in some individuals.

Vibriance Vitamin C Serum Reviews

As I looked through YouTube for unsponsored reviews of this product, I could not find any! The most popular one seems to be the one below:

However, it should be noted that the user in this video states that the brand sent her this product and is sponsoring her to review it.

So, take that for what it’s worth and assess any potential bias that may exist.

Better Business Bureau Reviews of Vibriance Vitamin C Serum

BBB ratings are a mix. There are some very good reviews of the product:

BBB Good reviews of vibriance super c serum


And some negative ones:

BBB negative reviews of vibriance super c serum

more negative BBB review of vibriance super c serum


My Recommended Clean Skincare Picks

Full transparency – The products I recommend below are affiliate links – I may earn a small commission at no additional cost to you if you decide to purchase through these links.

As you can see from my reviews, I will not recommend products I won’t use on myself.

With that said, here are my recommendations:

My strong recommendation is Annie Mak Vitamin C serum.

The product is clean, and I love the fact that the brand provides an instantly viewable third-party certificate of analysis for each product right there on the product page.

You can purchase the product directly from the official website at this link.

Annie Mak’s Reverse Anti-Aging Serum has also earned highly positive reviews. rates this product 4.74/5 stars at the time of this writing!

Click here to purchase the complete skin rejuvenation kit with a 36% discount.

My top recommendation for your moisturizer needs is CLEARSTEM™ Skincare’s HYDRAGLOW™ Stem Cell Moisturizer.

This product contains bakuchiol, which has high level of research backing to show its ability to reduce age-related wrinkles and photoaging.

In this 2019 randomized controlled trial, one group of participants applied bakuchiol 0.5% cream twice daily and another group applied retinol 0.5% cream daily.

After 12 weeks, both groups were observed to have reduced wrinkles and hyperpigmentation with no statistical difference between them.

However, what’s notable is that the retinol group experienced more facial scaling and stinging.

The best part, you don’t need a prescription to use CLEARSTEM’s HYDRAGLOW.

If interested, you can purchase HYDRAGLOW at the company’s official website here.

Also, you can save by applying my discount code GA15 to receive 15% off every order!

Oral Collagen

For improving skin hydration and elasticity, oral intake of collagen is superior.

I am particularly proud and privileged to be working with an absolutely amazing company – BUBS Naturals.

This company was founded to honor the memory and legacy of a National Hero – Former Navy Seal Glen “Bub” Doherty, who was killed in action while defending his brothers in Benghazi, Libya, on September 12, 2012.

The movie “13 Hours: The Secret Soldiers of Benghazi” tells the story of Bub and his valiant teammates fighting against armed terrorists during the assault on the State Department’s Mission Facility.

You can read more about Bub on the CIA website.

Click on the link to read my in-depth BUBS Naturals review.

Bubs Collagen Protein has earned my highest recommendation because it only contains protein and no other additives or artificial sweeteners.

If you use my discount code GA20 at checkout, you will get a 20% discount! 

At the time of this writing, Bubs protein powder costs $39.95 and provides 28 servings per container.

With your 20% discount, the per-serving price is $1.14!

If you are interested, please check out Bubs products at this link on their official website.

Transparent Labs is another company I trust and recommend for all your dietary supplement needs.

True to the company’s name, all reporting of product formulas, dosing, and 3rd party lab testing is completely transparent and listed on its official website!

Their products are not cheap because they do not cut corners in the formulation and production processes.

I personally take many of the supplements in their product line.

You get the pure product, that’s it!

I suggest their Grass-Fed Collagen Hydrolysate Powder without reservation for improving skin elasticity and hydration due to the huge presence of science-backed literature supporting its use.


In conclusion, while Vibriance Super C Serum may have some positive customer reviews, it’s important to consider the questionable claim about  3-O-Ethyl Ascorbic Acid. 

Furthermore, including potentially harmful ingredients such as triethanolamine, phenoxyethanol, and ethylhexylglycerin raises red flags for those seeking clean skincare options.

While individual experiences may vary, it’s always advisable to thoroughly research a product and its brand before making a purchase.

In this case, alternative clean skincare options are available that have a more transparent approach and use safer ingredients.

It’s recommended to explore other brands that prioritize ingredient integrity and have a track record of delivering effective skincare products.

Your skin deserves the best, so choose products that align with your values and meet your skincare needs.

Related Post