Can You Crush Tylenol?
Written By Kobi Nathan, Pharm.D., M.Ed., CDP, BCGP, AGSF
Sleep Disorders
June 8, 2023

Can you crush Tylenol?

You can crush most Tylenol (acetaminophen or paracetamol) products except capsules, liquid gels, and extended-release formulations.

Read on to learn why…

Have you ever struggled with swallowing a pill and wondered if crushing it might make things easier? You’re not alone.

Many people have difficulty taking medications in their original form, especially with large tablets like Tylenol. This is particularly relevant to certain older adults or people with brain damage.

Dysphagia, or difficulty swallowing, is a major medical problem that can lead to choking, aspiration pneumonia (as when food or liquid goes into your airway), resultant poor nutrition, declining health, and decreased quality of life.

Stroke or Dementia can lead to this type of swallowing difficulty. In fact, dysphagia is one of the 10 signs death is near for dementia patients.

In this article, we’ll explore whether or not it’s safe to crush acetaminophen, as well as alternative methods for managing pain.

We’ll delve into the various forms available and discuss which ones can be safely crushed, highlighting the risks and precautions associated with crushing Tylenol.

Finally, I’ll suggest alternative pain relief options that don’t require swallowing whole pills.

Different Types of Tylenol

Tylenol comes in different dosage forms, including regular strength, extra strength, and extended-release tablets.

Each type has a specific purpose and is designed to deliver the medication in a particular way for maximum effectiveness.

When considering crushing Tylenol tablets, it’s crucial to understand that some forms should not be crushed due to their unique design.

For instance, extended-release tablets are meant to release the active drug over time slowly – crushing them can release the entire dose at once and may lead to an overdose or other adverse effects.

On the other hand, regular strength and extra-strength Tylenol might be safe to crush if necessary for easier ingestion; however, it’s always best practice to take your medication as directed by your doctor before changing how you take it.

To keep it organized, here are the Tylenol products that should NOT be crushed:

  • Tylenol extended-release.
  • Tylenol Gelcaps.
  • Tylenol 8-hr Arthritis Pain.
  • Tylenol Coated Caps.
  • Any type of Tylenol liquid (for obvious reasons)

Generally, any formulation of acetaminophen that is an immediate-release tablet or caplet can be crushed.

Why can’t you crush these Tylenol products?

Let’s take a look at Tylenol Arthritis Pain – it has two layers – one for immediate release and the other for extended release.

These two layers work together to give you an immediate dose followed by a sustained release of 650 mg of acetaminophen over an 8-hour period.

Crushing this medication destroys these layers and causes all of the medication to be released into y our blood at once.

Now, this dose is not enough to cause major adverse effects such as liver damage (you need to consume greater than 4000 mg over a 24-hour period for that to occur). However, you may experience side effects such as nausea.

A word of caution – accidental overdose of Tylenol is one of the most common causes of liver injury and death.

It is actually very easy to overdose on acetaminophen – this is because a lot of OTC pain medicine have acetaminophen in them, especially combination medications such as Tylenol PM, commonly used to manage insomnia.

If you take this medication at night and regular Tylenol during the day, you can easily take too much and increase the risk of liver toxicity.

Watch the video below to learn how Tylenol overdose causes liver damage:


These night-time sleep aids are also dangerous for older adults. Read more about the dangers of anticholinergic effects in older adults in my articles on the 2023 Beers Criteria, Dementia, ZzzQuil vs NyQuil, and Polypharmacy.

For the other Tylenol products mentioned above, crushing the ones that have a coating on them will not result in a fine powder.

Rather, you will end up with large, uneven pieces that will make it even harder to swallow them.

Also, they may have a very unpleasant taste and can irritate your throat when swallowed.

Safe Methods for Crushing Tylenol

There are several ways to safely and effectively crush Tylenol.

Pill pulverizers or pill crushers are specifically designed for this purpose and provide a safe method for breaking down tablets into a fine powder.

These devices can be purchased at most pharmacies or online retailers and come with instructions on how to properly use them.

Here are two versions I recommend from Amazon (I may earn a small commission at no additional cost to you):

Additionally, you may opt for using a mortar and pestle, which is another reliable tool for crushing medications. I’m always partial to these…we pharmacists are intimately familiar with their use!

Again, another reminder…before attempting to crush any medication, always check the label to ensure that it is safe to do so – don’t crush the extended-release and or coated tablets!

If you’re unsure whether it’s appropriate to crush a particular tablet, consult your healthcare provider or pharmacist first.

Ways to get pain relief without crushing

You can also easily avoid the hassle of crushing tablets by using the oral suspension liquid formulation of Tylenol instead.

Most of these medications are marketed toward children, but there is no reason why adults shouldn’t be able to take them. The medication and strength are the same, and all you have to do is ensure you are taking the appropriate adult dose.

There are also chewable and specially formulated quick-dissolve forms of acetaminophen, which are much more palatable than crushing regular Tylenol.


Frequently Asked Questions

What is the difference between Tylenol and acetaminophen?

If you are talking about regular Tylenol, there is no difference. Acetaminophen is simply the generic name for brand name Tylenol.

Are there specific situations where crushing Tylenol is necessary or recommended?

In certain situations, crushing Tylenol may be necessary or even recommended. For instance, if you’re caring for someone who has difficulty swallowing pills or is using a feeding tube, crushing the medication can make it easier to administer.

How does crushing Tylenol compare to other methods of administering the medication, such as dissolving it in water or using a chewable form?

Crushing the medication can potentially change its release rate, leading to a quicker onset of effects that may not last as long.

In contrast, dissolving Tylenol in water or opting for a chewable form can provide a more controlled and even distribution of the active ingredient throughout your body.

This alternative method is also gentler on your stomach lining and can minimize any potential irritation caused by direct contact with crushed medication.



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